Hashimotos Thyroiditis
- 15 November 1962
- journal article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 267 (20) , 1015-1020
- https://doi.org/10.1056/nejm196211152672004
Abstract
BECAUSE high titers of circulating thyroid antibodies are present in the serums of patients with Hashimoto's thyroiditis, and a similar lymphocytic thyroiditis occurs in animals immunized with Freund's adjuvant and saline extracts of homologous thyroid glands, Hashimoto's thyroiditis has been considered an autoimmune disease.1 , 2 Cortisol (hydrocortisone) or cortisol-like compounds3 , 4 have been used in the treatment of other diseases that some investigators believe are associated with autoimmunity. Therefore, we treated 3 adolescent females with Hashimoto's thyroiditis for six months with pharmacologic doses of cortisone. This was done in an attempt to disrupt the autoimmune process and the possible progressive destruction of . . .Keywords
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