Erythrocyte Cholinesterase Activity in Hemolytic Anemias

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Abstract
Summary: The erythrocyte cholinesterase activity was studied in 41 thalassemic children, 15 cases of microdrepanocytosis (sickle cellthalassemia disease), 13 cases with favism, children with autoimmune hemolytic anemia, 2 cases of congenital spherocytosis, 2 children with aplastic anemia and 4 with iron deficiency anemia, as well as in children with pulmonary hemosiderosis. The mean activity of the red cell acetylcholinesterase in thalassemics was lower than normal, although a considerable overlapping of the values existpd in 25 % the population of the anemic and control groups. The enzyme activity was found to be consistently low in the three cases of autoimmune hemolytic anemia studied, while there were no significant changes in the other hemolytic anemias.