Germinal center architecture disturbance during Plasmodium berghei ANKA infection in CBA mice
Open Access
- 16 May 2007
- journal article
- Published by Springer Nature in Malaria Journal
- Vol. 6 (1) , 59
- https://doi.org/10.1186/1475-2875-6-59
Abstract
Immune responses to malaria blood stage infection are in general defective, with the need for long-term exposure to the parasite to achieve immunity, and with the development of immunopathology states such as cerebral malaria in many cases. One of the potential reasons for the difficulty in developing protective immunity is the poor development of memory responses. In this paper, the potential association of cellular reactivity in lymphoid organs (spleen, lymph nodes and Peyer's patches) with immunity and pathology was evaluated during Plasmodium berghei ANKA infection in CBA mice.Keywords
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