Isolation and characterization of fusaproliferin, a new toxic metabolite from Fusarium proliferatum
- 1 January 1995
- journal article
- Published by Wiley in Natural Toxins
- Vol. 3 (1) , 17-20
- https://doi.org/10.1002/nt.2620030105
Abstract
A new toxic sesterterpene, named fusaproliferin, was purified from corn kernel cultures (120 mg/kg dry culture) of a strain of Fusarium proliferatum isolated from corn ear rot in northern Italy. The stain, designated ITEM-1494, also produced fumonisin B1 (1.500 mg/kg dry culture) and beauvericin (90 mg/kg dry culture), but not moniliformin. To monitor toxicity, the brine shrimp assay was used throughout the isolation procedure. Fusaproliferin had a molecular formula of C27H40O5, and it is the first sesterterpene isolated from a Fusarium species.Keywords
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