Familial Thrombosis Due to Antithrombin III Deficiency in a Greek Family
- 1 January 1977
- journal article
- research article
- Published by S. Karger AG in Acta Haematologica
- Vol. 57 (1) , 47-54
- https://doi.org/10.1159/000207859
Abstract
A Greek family with hereditary antithrombin III (AT III) deficiency associated with venous thrombosis is reported. 5 members of the family were affected. In these patients, AT III and heparin cofactor activities were decreased. Immunoreactive AT III showed a positive correlation to both AT III and heparin cofactor activities. α2-Macroglobulin and α1-antitrypsin were normal. The pattern of inheritance of the defect is autosomal dominant.Keywords
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