ANTHELMINTIC EFFICACY OF IVERMECTIN GIVEN INTRAMUSCULARLY IN HORSES

  • 1 January 1982
    • journal article
    • research article
    • Vol. 43  (1) , 145-148
Abstract
The anthelinthic activity of ivermectin was evaluated in 18 female horses with naturally acquired parasitic infections. Horses were treated once (i.m.) with vehicle only (n = 6), 200 .mu./kg of body weight (n = 6), and 300 .mu.g/kg (n = 6). Efficacy of both dosages of ivermectin was > 99% against Gasterophilus spp., 100% against Trichostrongylus axei, Habronema muscae, H. majus and Draschia megastoma, 98-99% against adult cyathostomes, 86-97% against 4th-stage cyathostomes and 100% against adult large strongyles. Although ivermectin was incomplete in its activity against arterial stages of Strongylus vulgaris, it was effective against microfilariae of Onchocerca spp. Adverse local or systemic reactions were not observed due to treatment with ivermectin.