Chromosome Abnormality in Rat Leukemia Induced by 7,12-Dimethylbenz[ a ]anthracene
- 24 November 1967
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 158 (3804) , 1058-1059
- https://doi.org/10.1126/science.158.3804.1058
Abstract
A high percentage of consistent chromosome abnormality, trisomy of the longest telocentric chromosome, was found in leukemias induced in rats of the Long-Evans strain by pulse doses of 7,12-dimethylbenz[ a ]anthracene. Cells with this abnormality were large, immature, and mononuclear and tended toward erythroblastic maturation.This publication has 8 references indexed in Scilit:
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