Exstrophy of the cloaca in a 47,XXX child: Review of genitourinary malformations in triple‐X patients

Abstract
Cloacal exstrophy, unilateral renal agenesis, and Müllerian anomalies occurred in a live‐born infant with a 47,XXX chromosome constitution. The patient extends the range of genitourinary anomalies reported in triple‐X patients. Screening asymptomatic patients for urinary tract abnormalities may be useful in searching for silent malformations potentially associated with this karyotype.