Prediction of survival in glioma patients by means of positron emission tomography
- 1 June 1985
- journal article
- Published by Journal of Neurosurgery Publishing Group (JNSPG) in Journal of Neurosurgery
- Vol. 62 (6) , 816-822
- https://doi.org/10.3171/jns.1985.62.6.0816
Abstract
✓ The aim of this study was to determine whether positron emission tomography (PET) with fluorine-18 (18F)-2-deoxyglucose (FDG) can be used as a prognostic test in patients with high-grade cerebral gliomas, regardless of the treatment given. Forty-five patients with astrocytoma Grade III or IV were included in this analysis. The mean survival time of patients with tumors exhibiting high glucose utilization as determined by PET-FDG was 5 months, whereas patients with gliomas showing lower glucose utilization had a mean survival period of 19 months. It is postulated that PET-FDG scans reflect the biological behavior of high-grade astrocytomas and may be used to predict the survival time of patients harboring such neoplasms.Keywords
This publication has 28 references indexed in Scilit:
- Issues in the in vivo measurement of glucose metabolism of human central nervous system tumorsAnnals of Neurology, 1984
- Literature referencesJournal of Computed Tomography, 1981
- Prognostic significance of the pretreatment CT scan on time to progression for patients with malignant gliomasJournal of Neurosurgery, 1980
- Computerized tomography as a possible aid to histological grading of supratentorial gliomasJournal of Neurosurgery, 1977
- Enzymology of Cancer CellsNew England Journal of Medicine, 1977
- Über die Atmung von menschlichen Hirntumoren und Hirngewebe in vitroActa Neurochirurgica, 1961
- Nonparametric Estimation from Incomplete ObservationsJournal of the American Statistical Association, 1958
- Nonparametric Estimation from Incomplete ObservationsJournal of the American Statistical Association, 1958
- On the Origin of Cancer CellsScience, 1956