Relationship Between Avian and Mammalian Anti-Müllerian Hormones
Open Access
- 1 March 1977
- journal article
- research article
- Published by Oxford University Press (OUP) in Biology of Reproduction
- Vol. 16 (2) , 267-273
- https://doi.org/10.1095/biolreprod16.2.267
Abstract
Eight-day-old chick Müllerian ducts were cultured 4 days in the presence of testosterone (0.4 to 17.8 µM) in the medium and in association with avian and mammalian fetal testicular tissue. Müllerian regression was readily produced by homospecific fetal testicular tissue, but neither by testosterone nor by rat or calf fetal testicular tissue. However, chick embryonic testes completely inhibited rat fetal Müllerian ducts after 3 days in coculture. These results indicate that the factor responsible for Müllerian inhibition in chick embryos is neither testosterone nor a molecule identical to rat or calf anti-Müllerian hormone. However, the fact that chick anti-Müllerian hormone is biologically active in rats suggests that avian and mammalian hormones may be structurally related.This publication has 4 references indexed in Scilit:
- Plasma testosterone levels in the chick embryoGeneral and Comparative Endocrinology, 1975
- Pituitary growth hormones: further evidence for evolutionary conservatism based on immunochemical studies.Proceedings of the National Academy of Sciences, 1975
- FORMATION OF STEROIDS BY THE EQUINE FOETAL TESTISJournal of Endocrinology, 1967
- CLONAL GROWTH OF MAMMALIAN CELLS IN A CHEMICALLY DEFINED, SYNTHETIC MEDIUMProceedings of the National Academy of Sciences, 1965