Acylases in Plasma of Hamsters with Experimental Hepatitis

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Abstract
After the administration of D-galactosamine to golden Syrian hamsters, a rapid, but short-lived, increase in acylase I and Co-activated acylase (AA-Co) activity was noted in the blood plasma, but not in the liver. In the plasma of control hamsters, only form 2 AA-Co was identified, but, during experimental hepatitis, the appearance of form 1 was observed. Only form 2 hamster enzyme is strongly inhibited by .alpha.-hydroxyisocaproil-tyrosine and reacts with antihuman form 2 antibody.