TREATING EXTRAPYRAMIDAL REACTIONS - SOME CURRENT ISSUES
- 1 September 1987
- journal article
- research article
- Vol. 48, 24-27
Abstract
"Extrapyramidal" reactions to antipsychotic drugs include acute dystonias, akathisia, Parkinson''s syndrome, and tardive dyskinesia. Recent research suggests efficacy of prophylactic antiparkinson drugs in diminishing the incidence of acute dystonia in high-risk patients, although the use of lower neuroleptic doses also might lower the risk and cause fewer unwanted effects. New in the treatment of a kathisia is the use of beta-blockers, specifically propranolol (Inderal and others). Many patients require maintenance antiparkinson drug therapy during prolonged antipsychotic drug treatment. There is no effective treatment for tardive dyskinesia, the prevalence of which may be growing, with an estimated annual incidence of new cases of 3%-4%; the elderly and patients with affective illness may be at greatest risk. Clinicians are also attending to the related syndrome of tardive dystonia.This publication has 9 references indexed in Scilit:
- A Controlled Assessment of Propranolol in the Treatment of Neuroleptic-Induced AkathisiaThe British Journal of Psychiatry, 1986
- ANTICHOLINERGIC AGENTS FOR PROPHYLAXIS OF NEUROLEPTIC-INDUCED DYSTONIC REACTIONS - A PROSPECTIVE-STUDY1986
- Prevention of acute dystonic reactions in patients beginning high- potency neuroleptics [published erratum appears in Am J Psychiatry 1986 Sep;143(9):1204]American Journal of Psychiatry, 1986
- EVALUATION OF THE NEED FOR PROPHYLACTIC ANTIPARKINSONIAN MEDICATION IN PSYCHOTIC-PATIENTS TREATED WITH NEUROLEPTICS1986
- USE OR ABUSE OF ANTIPARKINSONIAN DRUGS BY PSYCHIATRIC-PATIENTS1986
- Use of clonidine in treating neuroleptic-induced akathisiaPsychiatry Research, 1984
- Tardive dystoniaNeurology, 1982
- Adverse effects of antiparkinson drug withdrawalAmerican Journal of Psychiatry, 1981
- The need for continuous use of antiparkinsonian medication with chronic schizophrenic patients receiving long-term neuroleptic therapyAmerican Journal of Psychiatry, 1981