Detection of Low Levels of the Amorphous Phase in Crystalline Pharmaceutical Materials by Thermally Stimulated Current Spectrometry
- 1 January 2001
- journal article
- Published by Springer Nature in Pharmaceutical Research
- Vol. 18 (1) , 98-103
- https://doi.org/10.1023/a:1011087012826
Abstract
Purpose. To demonstrate the applicability of thermally stimulated current (TSC) spectrometry for the detection of low levels of the amorphous phase in crystalline pharmaceutical materials. Methods. A...Keywords
This publication has 11 references indexed in Scilit:
- The Quantitative Analysis of Crystallinity Using FT-Raman SpectroscopyPharmaceutical Research, 1998
- Characterisation of the Glass Transition of an Amorphous Drug Using Modulated DSCPharmaceutical Research, 1998
- Identification of drugs in pharmaceutical dosage forms by X-ray powder diffractometryJournal of Pharmaceutical and Biomedical Analysis, 1997
- Characteristics and Significance of the Amorphous State in Pharmaceutical SystemsJournal of Pharmaceutical Sciences, 1997
- How Does Residual Water Affect the Solid-state Degradation of Drugs in the Amorphous State?Journal of Pharmaceutical Sciences, 1996
- Dielectric Analysis in the Characterization of Amorphous Pharmaceutical Solids. 1. Molecular Mobility in Poly(vinylpyrro1idone)-Water Systems in the Glassy StateJournal of Pharmaceutical Sciences, 1995
- Molecular Mobility of Amorphous Pharmaceutical Solids Below Their Glass Transition TemperaturesPharmaceutical Research, 1995
- Differential Thermal, Solubility, and aging Studies on various Sources of Digoxin and Digitoxin Powder: Biopharmaceutical ImplicationsJournal of Pharmaceutical Sciences, 1979
- Estimation of the degree of crystallinity in digoxin by X-ray and infrared methodsJournal of Pharmacy and Pharmacology, 1977
- Changes in crystallinity and solubility on comminution of digoxin and observations on spironolactone and oestradiolJournal of Pharmacy and Pharmacology, 1976