Abstract
At least part of the Z-histidine monohydrochloride injected sub-cutaneously into rabbits was decomposed and excreted in the urine as the corresponding unsaturated acid (uro-canic). After dl-histidine monohydrochloride injection some d-histidine was isolated from the urine, but no urocanic acid. Oidium lactis produced imidazole pro-pionic acid from Z-histidine. The conversion of histidine by the animal organism to the unsaturated acid is noteworthy as is also the production of the corresponding saturated non-amino acid by Oidium lactis; under similar conditions most amino acids would undergo conversion to the corresponding keto or hydroxy acid in the animal body and conversion to the corresponding hydroxy acid by Oidium lactis.