ECG Changes during Lithium Therapy
- 12 January 1984
- journal article
- research article
- Published by Wiley in Acta Medica Scandinavica
- Vol. 216 (1) , 101-104
- https://doi.org/10.1111/j.0954-6820.1984.tb03777.x
Abstract
The influence of long-term Li treatment on the ECG was investigated in 53 consecutive patients. An ECG was recorded prior to and 4 and 12 mo. after institution of Li therapy. The most frequently observed change during treatment was flattening or inversion of the T wave. Heart rate decreased and P-Q interval increased slightly during therapy. There was no change in the S-T segment or the Q-T interval corrected for heart rate. Well monitored Li treatment of patients with serum Li concentrations of .apprx. 0.6 mmol/l apparently does not cause serious ECG abnormalities. In the absence of symptoms or signs of heart disease, routine monitoring of ECG is not necessary during Li treatment.Keywords
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