The pure antiestrogen ICI 182780 is more effective in the induction of apoptosis and down regulation of BCL-2 than tamoxifen in MCF-7 cells.
- 1 November 1999
- journal article
- Published by Springer Nature in Breast Cancer Research and Treatment
- Vol. 58 (2) , 87-97
- https://doi.org/10.1023/a:1006338123126
Abstract
No abstract availableKeywords
This publication has 25 references indexed in Scilit:
- A realistic clinical perspective of tamoxifen and endometrial carcinogenesisEuropean Journal Of Cancer, 1996
- Possible mechanisms in the emergence of tamoxifen-resistant breast cancerAnti-Cancer Drugs, 1995
- Comparison of the Effects of a Pure Steroidal antiestrogen With Those of Tamoxifen in a Model of Human Breast CancerJNCI Journal of the National Cancer Institute, 1995
- MCF‐7 human mammary adenocarcinoma cell death in vitro in response to hormone‐withdrawal and dna damageInternational Journal of Cancer, 1995
- Use of tamoxifen for breast cancer: twenty-eight years later.Journal of Clinical Oncology, 1995
- Should clinicians be concerned about the carcinogenic potential of tamoxifen?European Journal Of Cancer, 1994
- Molecular Mechanisms of Resistance to Tamoxifen Therapy in Breast CancerArchives of Surgery, 1993
- Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell deathNature, 1990
- The pharmacology and clinical uses of tamoxifenPharmacology & Therapeutics, 1984
- Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue KineticsBritish Journal of Cancer, 1972