Prestone Gallstone Disease — Is Therapy Safe?

Publisher Website
Google Scholar
Abstract
The pathogenesis of cholesterol gallstones has been divided into three stages.1 The first stage involves the formation of abnormal bile supersaturated with cholesterol, the second stage, the nucleation and precipitation of the excess cholesterol as cholesterol crystals, and the third the growth or conglomeration of these crystals into macroscopic stones capable of producing clinical gallstone disease.Recently, Sampliner et al.2 showed that the true age-specific prevalence of gallstones in Pima Indian men increased only gradually between the ages of 15 and 65 but in women jumped from less than 1 per cent at 18 to greater than 75 per . . .