The excretion of an anti-pernicious anaemia principle in the urine

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Abstract
Extracts were prepared from normal urines and from the urines of treated patients with remitting pernicious anemia which will initiate normal remissions of the disease when given intramusc. to relapsing patients with pernicious anemia. Similar extracts prepared from the urines of untreated relapsing cases of pernicious anemia did not possess such anti-pernicious anemia activity when tested clinically. This urinary anti-pernicious anemic principle although showing a similar clinical action may or may not be identical with the liver principle. This active material is present in the urine in relatively small amts.