Synthesis of Photoactive p-Azidotetrafluorophenylalanine Containing Peptide by Solid-Phase Fmoc Methodology
- 9 November 2002
- journal article
- letter
- Published by American Chemical Society (ACS) in Organic Letters
- Vol. 4 (25) , 4467-4469
- https://doi.org/10.1021/ol026998f
Abstract
[structure: see text] N-Fmoc-L-p-azidotetrafluorophenylalanine was prepared from achiral starting materials using an acetamidomalonate synthesis and enzymatic resolution. A photoactive peptide containing this fluorinated residue could be assembled using solid-phase Fmoc chemistry.Keywords
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