Cellular mechanisms of oxygen toxicity.

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Abstract
The investigations reviewed in this article illustrate the variety of the toxic effects of O2 seen in living organisms exposed to concentrations of O2 greater than those to which they are adapted. Clearly, O2 is a substance universally toxic to living cells. It is only by developing special defense mechanisms that animals and plants can survive the ever-present oxidizing potential of the O2 in their surroundings.

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