Side Products of Routine Plasma Fractionation
- 5 March 1979
- journal article
- research article
- Published by Wiley in Vox Sanguinis
- Vol. 36 (3) , 142-149
- https://doi.org/10.1111/j.1423-0410.1979.tb04415.x
Abstract
Cholinesterase (EC 3.1.1.8) for intravenous use has been obtained from fraction IV, a by‐product of ethanol fractionation. A four‐step procedure has been developed associating precipitation by Rivanol® and PEG 4000 with chromatography on DEAE‐cellulose. The yield corresponds to 30–35% of the activity found in fraction IV. Vials containing 5000 U of CHE stabilized by 2.5% albumin have been prepared. The pyrogen‐free product is well tolerated in the human.This publication has 18 references indexed in Scilit:
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