Not just research tools—proteasome inhibitors offer therapeutic promise
- 1 April 2002
- journal article
- editorial
- Published by Springer Nature in Nature Medicine
- Vol. 8 (4) , 338-340
- https://doi.org/10.1038/nm0402-338
Abstract
No abstract availableKeywords
This publication has 15 references indexed in Scilit:
- Proteasome inhibition reduces superantigen-mediated T cell activation and the severity of psoriasis in a SCID-hu modelJournal of Clinical Investigation, 2002
- Proteasome inhibition in cancer: Development of PS-341Seminars in Oncology, 2001
- NF-κB signaling pathways in mammalian and insect innate immunityGenes & Development, 2001
- The 26S Proteasome: A Molecular Machine Designed for Controlled ProteolysisAnnual Review of Biochemistry, 1999
- DEGRADATION OF CELL PROTEINS AND THE GENERATION OF MHC CLASS I-PRESENTED PEPTIDESAnnual Review of Immunology, 1999
- THE UBIQUITIN SYSTEMAnnual Review of Biochemistry, 1998
- Nuclear Factor-κB — A Pivotal Transcription Factor in Chronic Inflammatory DiseasesNew England Journal of Medicine, 1997
- Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I moleculesCell, 1994
- The ubiquitinproteasome pathway is required for processing the NF-κB1 precursor protein and the activation of NF-κBCell, 1994
- A soluble ATP-dependent proteolytic system responsible for the degradation of abnormal proteins in reticulocytes.Proceedings of the National Academy of Sciences, 1977