Cytotoxic Diarylheptanoids from the Roots of Juglans mandshurica
- 18 September 2002
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of Natural Products
- Vol. 65 (11) , 1707-1708
- https://doi.org/10.1021/np0201063
Abstract
A new (2) and three known diarylheptanoids (1, 3, and 4), along with one known sesquiterpenoid (5), were isolated from the roots of Juglans mandshurica, and their structures were elucidated on the basis of spectroscopic studies. Four of these compounds (2−5) exhibited moderate cytotoxicities against human colon carcinoma and human lung carcinoma cell lines with IC50's ranging from 2 to 25 μg/mL.Keywords
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