SUCROSE FEEDING IN MAN

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Abstract
In four patients with hyperlipoproteinemia and in one with a normal serum lipoprotein pattern 800 kcal of the daily caloric intake were replaced by sucrose for two weeks. Studies of the adipose tissue metabolism in vitro showed that the lipid synthesis from glucose, the basal as well as the noradrenaline‐stimulated lipolysis, were considerably increased as compared to the controls. Furthermore, no antilipolytic effect of a physiological concentration of insulin was found. It was suggested that sucrose feeding induces changes in adipose tissue metabolism which may be of importance for the increased triglyceride levels noted in these patients.