Rectosigmoid Motility Response to Sham Feeding in Irritable Bowel Syndrome: Evidence of a Cephalic Phase

1 January 1989

journal article
research article
Published by Taylor & Francis in Scandinavian Journal of Gastroenterology

Vol. 24 (1) , 53-56
https://doi.org/10.3109/00365528909092239

Abstract

Rectosigmoid pressure recordings by means of open-ended perfused catheters were performed on 21 patients with the irritable bowel syndrome (IBS). Motility indexes were calculated in resting conditions, after sham feeding, after a meal, and after 0.5 mg neostigmine intravenously. Each step of stimulation caused a significantly increased motility index compared with the previous step (p < 0.01). the increase in rectosigmoid pressure activity after sham feeding indicates the existence of a cephalic phase in the postprandial motor response of the colon in IBS.

Keywords

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