The Excision Mechanism in Reverse Transcriptase: Pyrophosphate Leaving and Fingers Opening are Uncoupled Events with the Analogues AZT and d4T
- 22 September 2007
- journal article
- research article
- Published by American Chemical Society (ACS) in The Journal of Physical Chemistry B
- Vol. 111 (41) , 12032-12039
- https://doi.org/10.1021/jp0746594
Abstract
No abstract availableKeywords
This publication has 23 references indexed in Scilit:
- GROMACS: Fast, flexible, and freeJournal of Computational Chemistry, 2005
- Nonnucleoside Inhibitor Binding Affects the Interactions of the Fingers Subdomain of Human Immunodeficiency Virus Type 1 Reverse Transcriptase with DNAJournal of Virology, 2004
- ATP-Dependent Removal of Nucleoside Reverse Transcriptase Inhibitors by Human Immunodeficiency Virus Type 1 Reverse TranscriptaseAntimicrobial Agents and Chemotherapy, 2002
- Refined model for primer/template binding by HIV-1 reverse transcriptase: pre-steady-state kinetic analyses of primer/template binding and nucleotide incorporation events distinguish between different binding modes depending on the nature of the nucleic acid substrate 1 1Edited by J. KarnJournal of Molecular Biology, 1999
- Structure and functional implications of the polymerase active site region in a complex of HIV-1 RT with a double-stranded DNA template-primer and an antibody fab fragment at 2.8 Å resolutionJournal of Molecular Biology, 1998
- VMD: Visual molecular dynamicsJournal of Molecular Graphics, 1996
- 2.2 å resolution structure of the amino-terminal half of HIV-1 reverse transcriptase (fingers and palm subdomains)Structure, 1994
- Atomic charges derived from semiempirical methodsJournal of Computational Chemistry, 1990
- An approach to computing electrostatic charges for moleculesJournal of Computational Chemistry, 1984
- Comparison of simple potential functions for simulating liquid waterThe Journal of Chemical Physics, 1983