Prothymosin α is an evolutionary conserved protein covalently linked to a small RNA
- 6 November 1989
- journal article
- Published by Wiley in FEBS Letters
- Vol. 257 (2) , 247-250
- https://doi.org/10.1016/0014-5793(89)81544-3
Abstract
A 13 kDa protein, covalently linked to a small RNA from the cytoplasm of mouse cells, was studied. Sequence analysis of its tryptic peptides revealed that the RNA‐linked protein is identical to prothymosin α. Very similar RNA‐protein complexes were identified in human, bovine and yeast cells. Tryptic peptide maps of 125I‐labelled RNA‐linked proteins of diverse origin demonstrated their marked similarity, thus indicating high evolutionary conservation of prothymosin α from yeast to man.Keywords
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