Chromosome deletion at 11q23 in an abnormal child from a family with inherited fragility at 11q23
- 1 June 1987
- journal article
- research article
- Published by Springer Nature in Human Genetics
- Vol. 76 (2) , 202-204
- https://doi.org/10.1007/bf00284923
Abstract
A neonate with clinical features of the 11q23 deletion syndrome was apparently mosaic with the dominant cell line showing deletion of the chromosomal segment 11q23.3 to 11qter. The presence of a few lymphocytes with a normal karyotype indicates post-zygotic deletion of chromosome 11. The mother and brother of the propositus show folate-sensitive fragility at band 11q23.3. This case indicates in vivo deletion at a folate-sensitive fragile site.This publication has 13 references indexed in Scilit:
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