Immunization and Antibody Response in the Newborn Infant

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Abstract
THE pediatrician, general practitioner and public-health officer are concerned with early, safe, effective protection against diseases that can be prevented by the use of vaccines. The earliest time that adequate active immunization can be accomplished in infants is very difficult to determine, and in fact not finally decided for any of the immunizing agents commonly used in infancy,1 2 3 4 5 although the basic processes involved in immunology are being pursued. Previous studies6,7 showed that children at three weeks of age can be effectively immunized against pertussis, tetanus and diphtheria. These studies demonstrated that protective levels of antibody responses could be obtained . . .