SULFAMETHAZINE RESIDUES IN UNCOOKED EDIBLE TISSUES OF PORK FOLLOWING RECOMMENDED ORAL-ADMINISTRATION AND WITHDRAWAL

  • 1 January 1980
    • journal article
    • research article
    • Vol. 44  (3) , 338-345
Abstract
Commercial feed rations containing sulfamethazine at the level of 110 ppm were fed for a period of 65 days to market pigs in a study simulating normal farm practices. The levels of sulfamethazine at the end of medication were in excess of 10 ppm in liver and kidney and up to 2.6 ppm in muscle tissues. Concentrations of sulfamethazine in tissues from pigs after withdrawal of medicated feed depleted to 0.1 ppm within 9 days. The rate of depletion was similar for all tissues. Storage of tissue samples at freezer temperature (-20.degree. C) for 30 days further reduces sulfamethazine levels by 3-20% of their original value.