Convulsants (benzylpenic'illin and pentylenetetrazol) on potential clamped myelinated axons from the rat
- 1 October 1980
- journal article
- research article
- Published by Wiley in Acta Physiologica Scandinavica
- Vol. 110 (2) , 145-148
- https://doi.org/10.1111/j.1748-1716.1980.tb06644.x
Abstract
The effect of 2 convulsants, benzylpenicillin and pentylenetetrazol, was tested in potential clamp experiments on single rat myelinated nerve fibers. Concentrations [10 mM] did not affect the permeability properties of the nodal membrane. The convulsive action is probably not mediated through changes in the excitability of central axons. [Benzylpenicillin and pentylenetetrazol are used in experimental models of epilepsy.].Keywords
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