Primary Progressive Multifocal Leukoencephalopathy
- 1 October 1972
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Neurology
- Vol. 27 (4) , 357-360
- https://doi.org/10.1001/archneur.1972.00490160085012
Abstract
In case of primary progressive multifocal leukoencephalopathy, light microscopy demonstrated amphophilic intranuclear inclusion bodies, and electron microscopy confirmed the presence of papova-like and myxovirus in glial cells. The hypothesis is offered that the disease is caused by a slow virus, not necessarily having an altered immune mechanism as a prerequisite for its propagation, and that altered immunity may provide a more favorable background for its proliferation.Keywords
This publication has 4 references indexed in Scilit:
- Slow Virus Diseases of the Central Nervous SystemAmerican Journal of Clinical Pathology, 1971
- Primary progressive multifocal leukoencephalopathyNeurology, 1971
- Particles Resembling Papova Viruses in Human Cerebral Demyelinating DiseaseScience, 1965
- Progressive Multifocal LeukoencephalopathyNew England Journal of Medicine, 1961