The Effect of Duodenal Juice on the Intrinsic Factor (IF) Activity in Gastric Juice
- 1 January 1975
- journal article
- Published by Taylor & Francis in Scandinavian Journal of Gastroenterology
- Vol. 10 (1) , 49-53
- https://doi.org/10.1080/00365521.1975.12096922
Abstract
Duodenal juice, collected during basal conditions and during stimulation by pentagastrin, secretin, or cholecystokinin, was incubated with neutralized normal gastric juice. High concentrations of bile or proteolytic activity were accompanied by decrease of IF concentration. The inhibition was time- and temperature-dependent, increased significantly at low pH values, and seemed to be partly due to competitive inhibition by unspecific vitamin B12-binding activity. The results are of importance for measurements of IF concentration in gastric juice.Keywords
This publication has 7 references indexed in Scilit:
- The Effect of Exogenous Secretin and Cholecystokinin (CCK) on Pentagastrin-Stimulated Intrinsic Factor (IF) Secretion in ManScandinavian Journal of Gastroenterology, 1974
- Haemoglobin - Coated Charcoal for Estimation of Gastric Intrinsic FactorScandinavian Journal of Gastroenterology, 1973
- The role of pancreatic exocrine secretions in the absorption of vitamin B12 and ironThe American Journal of Clinical Nutrition, 1973
- A component of human duodenal juice that affects intrinsic factorBiochemical Journal, 1969
- Biliary and Fecal Vit. B12 Excretion in Man. An Isotope Study.Experimental Biology and Medicine, 1958
- Action of Group Blocking Agents and Enzymes on Intrinsic Factor Preparations.Acta Chemica Scandinavica, 1958
- THE ESTIMATION OF PEPSIN, TRYPSIN, PAPAIN, AND CATHEPSIN WITH HEMOGLOBINThe Journal of general physiology, 1938