Base-Pairing Systems Related to TNA: α-Threofuranosyl Oligonucleotides Containing Phosphoramidate Linkages1
- 16 March 2002
- journal article
- letter
- Published by American Chemical Society (ACS) in Organic Letters
- Vol. 4 (8) , 1279-1282
- https://doi.org/10.1021/ol020015x
Abstract
(3‘NH)- and (2‘NH)-TNA, two isomeric phosphoramidate analogues of TNA (α-threofuranosyl-(3‘→2‘) oligonucleotides), are shown to be efficient Watson−Crick base-pairing systems and to undergo intersystem cross-pairing with TNA, RNA, and DNA.Keywords
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