Studies on macrocyclic lactone antibiotics. VII Structure of a phytotoxin "rhizoxin" produced by Rhizopus chinensis.
- 1 January 1984
- journal article
- research article
- Published by Japan Antibiotics Research Association in The Journal of Antibiotics
- Vol. 37 (4) , 354-362
- https://doi.org/10.7164/antibiotics.37.354
Abstract
A new 16-membered macrolide designated as rhizoxin was isolated as a toxin produced by R. chinensis, the causal agent of rice seedling blight. The skeleton structure was determined by detailed NMR spectroscopic investigation of this compound and of its derivatives. Rhizoxin at 10 ng/ml induced abnormal swelling of rice seedling roots, a characteristic symptom of this disease. This compound exhibited potent antifungal activity but little against bacteria.This publication has 1 reference indexed in Scilit:
- Studies on macrocyclic lactone antibiotics. VI. Skeletal structure of copiamycin.The Journal of Antibiotics, 1982