Abstract
Ceratocystis stenoceras, usually parasitic on plants, was pathogenic for the hamster and mouse. Unicellular forms grown at 35°C. produced lesions in some animals. Passaged strains were always more virulent than wild strains. They did not form perithecia and are considered to be stable, asexual pathogenic mutants. Since they produced triangular pigmented spores they are indistinguishable from Sprothrix schenckii as regards morphology, physiology and pathogenicity. The experimentally produced disease was similar to experimental sprotrichosis. There were cigarand asteroid bodies. This suggested that Ceratocystis may be the cause of spontaneous sporotrichosis. If C. stenocera can change to S. schenckii, the experimental results so far obtained do not warrant the conclusion that the fungi are synonymous; a sexual stage of S. schenckii has still to be discovered.