Vitamin D supplements and 25-hydroxy vitamin D concentrations in the elderly.
- 1 October 1977
- Vol. 2 (6091) , 859-861
- https://doi.org/10.1136/bmj.2.6091.859
Abstract
Serial 25-hydroxy vitamin D (25-OHD) concentrations were measured in long-stay geriatric patients treated with vitamin D. Comparison between a treatment and a control group showed that a daily dose of 500 IU vitamin D produced a significant increase in 25-OHD levels by two months. The supplement had a striking effect when the initial 25-OHD level was low and very little effect when it was high. 25-OHD levels in subjects on 2000 IU vitamin D daily were only marginally higher than those in subjects on 500 IU. A dose of 500 IU vitamin D daily should therefore produce adequate blood 25-OHD concentrations in most old people, and probably prevent most cases of osteomalacia in the elderly--though a large-scale study is needed to confirm this.Keywords
This publication has 4 references indexed in Scilit:
- VITAMIN-D STATUS IN LONG-STAY GERIATRIC PATIENTSThe Lancet, 1975
- A Rapid Assay for 25-OH-Vitamin D3Without Preparative Chromatography*Journal of Clinical Endocrinology & Metabolism, 1974
- SEASONAL VARIATIONS IN SERUM 25-HYDROXYCHOLECALCIFEROL IN HEALTHY PEOPLEThe Lancet, 1974
- Seasonal Changes in Human Plasma Levels of 25-Hydroxyvitamin DNature, 1974