Reply
- 1 August 1978
- journal article
- Published by Elsevier in Gastroenterology
- Vol. 75 (2) , 347-348
- https://doi.org/10.1016/0016-5085(78)90448-1
Abstract
No abstract availableThis publication has 11 references indexed in Scilit:
- Mechanism for reduced drug clearance in patients with cirrhosisGastroenterology, 1978
- Hepatic clearance of drugs. III. Additional experimental evidence supporting the “wellstirred” model, using metabolite (MEGX) generated from lidocaine under varying hepatic blood flow rates and linear conditions in the perfused rat liverin situ preparationJournal of Pharmacokinetics and Biopharmaceutics, 1977
- Hepatic clearance of drugs. II. Experimental evidence for acceptance of the “well-stirred” model over the “parallel tube” model using lidocaine in the perfused rat liverin situ preparationJournal of Pharmacokinetics and Biopharmaceutics, 1977
- Hepatic clearance of drugs. I. Theoretical considerations of a “well-stirred” model and a “parallel tube” model. Influence of hepatic blood flow, plasma and blood cell binding, and the hepatocellular enzymatic activity on hepatic drug clearanceJournal of Pharmacokinetics and Biopharmaceutics, 1977
- Enzymatic elimination of substrates flowing through the intact liverJournal of Theoretical Biology, 1976
- Hepatic Elimination Kinetics: The Influence of Hepatic Blood Flow on Clearance DeterminationsScandinavian Journal of Clinical and Laboratory Investigation, 1976
- A physiological approach to hepatic drug clearanceClinical Pharmacology & Therapeutics, 1975
- Clearance concepts in pharmacokineticsJournal of Pharmacokinetics and Biopharmaceutics, 1973
- FACTORS AFFECTING DRUG METABOLISMAnnals of the New York Academy of Sciences, 1971
- Mathematical models, reality and resultsJournal of Theoretical Biology, 1965