Toxic Epidermal Necrolysis

Abstract
A DIFFUSE bullous eruption of acute onset associated with marked skin tenderness was described in 1956 by Lyell1 as well as Lang and Walker.2 Subsequently, Beare3 reviewed the literature and described. the clinical and histologic manifestations of 10 cases observed in Irish adults and children. Although many similar reports have appeared in the literature4 only a few such cases have been reported from America, and these have all been in specialty journals.5 It is likely that the syndrome has not been widely recognized in the United States. Therefore, the following classic example of toxic epidermal necrolysis has been annotated for . . .

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