Antibody to Nuclear Material Eluted from Isolated Spleen Vessels in Systemic Lupus Erythematosus
- 30 October 1970
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 170 (3957) , 550-551
- https://doi.org/10.1126/science.170.3957.550
Abstract
Splenic blood vessels were isolated from surrounding cells by treatment with trypsin and the use of ultrasound. This procedure retained vascular-bound immunoglobulins which were recovered by acid elution of vessels isolated from a patient with systemic lupus erythematosus. These eluted immunoglobulins reacted with material from cell nuclei as demonstrated by immunofluorescence.Keywords
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