Amino acid structure and “difficult sequences” in solid phase peptide synthesis
- 1 September 1992
- journal article
- Published by Wiley in International Journal of Peptide and Protein Research
- Vol. 40 (3-4) , 300-307
- https://doi.org/10.1111/j.1399-3011.1992.tb00305.x
Abstract
Deprotection peak profiles have been determined as a measure of internal aggregation during Fmoc-polyamide continuous flow solid phase synthesis. The results have been correlated with amino-acid structure and discussed in terms of minimising aggregation during synthesis.Keywords
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