Calcium and parathyroid disorders in children. Chronic renal failure and treatment with calcitriol
- 23 March 1979
- journal article
- research article
- Published by American Medical Association (AMA) in JAMA
- Vol. 241 (12) , 1242-1244
- https://doi.org/10.1001/jama.241.12.1242
Abstract
Progression of renal failure, represented by rising serum creatinine concentrations, was correlated with progressive elevation of serum parathyroid hormone (PTH) concentrations in 23 children. A significant linear relationship was established. Despite normal serum Ca concentrations in 11 children receiving maintenance hemodialysis, circulating PTH concentrations were elevated after 6 mo. Progressive deterioration with time occurred in all variables tested, at 6 mo. intervals. These complications were reversible with kidney transplantation or treatment with 0.25-2 .mu.g/day of calcitriol for 4-20 wk.This publication has 7 references indexed in Scilit:
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