A comparison between the release of fluoride from sodium fluoride lozenges and bone meal tablets

Publisher Website
Google Scholar
Abstract
The release of fluoride from a F-containing bone meal tablet and a chewable NaF lozenge to 0.5 M perchloric acid, deionized water and saliva was studied as a cariostatic agent. In acid, all the fluoride was released from the bone meal tablet (0.25 mg F), while there was a poor release in water and saliva (2-10%). The release from the NaF lozenge (0.25 mg F) was essentially complete in water, saliva and in acid. Following sucking and chewing on a NaF lozenge by dental students, the mean salivary fluoride concentration increased from 0.04 to 36 parts/106 5 min after intake. Concentrations exceeding the preintake level were still recorded after 20 min. With the bone meal tablet, only a slight increase (to 0.2 parts/106) in the salivary fluoride level was obtained.