SPONTANEOUS AND EXPERIMENTALLY INDUCED UPTAKE OF RADIOACTIVE IODINE IN METASTASES FROM THYROID CARCINOMA: A PRELIMINARY REPORT*†

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Abstract
In 14 unselected cases of metastatic thyroid carcinoma studied with radioactive iodine, uptake of the isotope was demonstrated in 8 (57%). The radioiodine uptake by the metastatic carcinoma was more closely correlated tp the degree of preceding thyroidectomy than to the histologic structure or "type" of the tissue. In cases in which initial studies with radioiodine do not show concn. in the metastases, such concn. may be induced by either thyroidectomy (surgical, radiation or chemical) or injns. of thyrotropic hormone.