Glia-Induced Morphological Differentiation in Neuroblastoma Cells
- 1 June 1973
- journal article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 70 (6) , 1894-1897
- https://doi.org/10.1073/pnas.70.6.1894
Abstract
Glial cells release a factor into their culture medium that induces a high degree of morphological differentiation in neuroblastoma cells under normal growth conditions. This phenomenon is not correlated with a change in intracellular adenosine 3':5'-cyclic monophosphate or in the rate of cell growth. Media from other cell lines tested induce less morphological differentiation or have no effect.Keywords
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