Requirement for hsp70 in the mitochondrial matrix for translocation and folding of precursor proteins
- 1 November 1990
- journal article
- Published by Springer Nature in Nature
- Vol. 348 (6297) , 137-143
- https://doi.org/10.1038/348137a0
Abstract
By analysis of a temperature-sensitive yeast mutant, a heat-shock protein in the matrix of mitochondria, mitochondrial hsp70 (Ssc1p), is found to be involved both in translocation of nuclear-encoded precursor proteins across the mitochondrial membranes and in (re)folding of imported proteins in the matrix.Keywords
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