Platelets and the immune continuum
Top Cited Papers
- 25 March 2011
- journal article
- review article
- Published by Springer Nature in Nature Reviews Immunology
- Vol. 11 (4) , 264-274
- https://doi.org/10.1038/nri2956
Abstract
Platelets are anucleate cells that are crucial mediators of haemostasis. Most immunologists probably don't think about platelets every day, and may even consider these cells to be 'nuisances' in certain in vitro studies. However, it is becoming increasingly clear that platelets have inflammatory functions and can influence both innate and adaptive immune responses. Here, we discuss the mechanisms by which platelets contribute to immunity: these small cells are more immunologically savvy than we once thought.Keywords
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