The reaction of Tetrazole with Phosphoramidites as a Model for the Nucleotide Coupling Step
- 1 October 1988
- journal article
- research article
- Published by Taylor & Francis in Nucleosides and Nucleotides
- Vol. 7 (5-6) , 763-767
- https://doi.org/10.1080/07328318808056326
Abstract
The mechanism of the tetrazole-activated coupling step in the synthesis of oligonucleotides via phosphorami-dites is studied with the help of model reactions.Keywords
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