Neurogenic Detrusor Areflexia: Correlation of Perineal Electromyography and Bethanechol Chloride Supersensitivity Testing

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Abstract
Patients [63] with detrusor areflexia were studied by cystometrography, perineal floor electromyography and bethanechol chloride supersensitivity testing. Of the patients, 48 had unequivocal evidence of neuropathy, while 15 were neurologically normal and served as controls. The bethanechol chloride supersensitivity test was positive in 98% of the patients and none of the controls, whereas neuropathic changes by electromyography were found in 67% of the patients and 7% of the controls. Evidently, the bethanechol chloride supersensitivity test is more sensitive and more specific than perineal floor electromyography in corroborating bladder neuropathy.