Human cell lines, derived from AHH-1 TK+/− human lymphoblasts, genetically engineered for expression of cytochromes P450

This publication has 20 references indexed in Scilit:

• Cytochrome P-450 hPCN3, a Novel Cytochrome P-450 IIIA Gene Product That Is Differentially Expressed in Adult Human Liver: cDNA and deduced amino acid sequence and distinct specificities of cDNA-expressed hPCN1 and hPCN3 for the metabolism of steroid hormones and cyclosporin
  Published by Elsevier ,2021
• A tobacco smoke-derived nitrosamine, 4-(methytnitrosamino)-1-(3-pyridyl)-1-butanone, is activated by multiple human cytocbrome P450s including the polymorphic human cytochrome P4502D6
  Carcinogenesis: Integrative Cancer Research, 1991
• The development of a human cell line stably expressing human CYP3A4: role in the metabolic activation of aflatoxin B₁ and comparison to CYP1A2 and CYP2A3
  Carcinogenesis: Integrative Cancer Research, 1991
• Human cytochrome P450IIA3: cDNA sequence role of the enzyme in the metabolic of promutagens comparison to nitrosamine activation by human cytochrome P450IIE1
  Carcinogenesis: Integrative Cancer Research, 1990
• Stable expression of human cytochrome P450IA2 cDNA in a human lymphoblastoid cell line: Role of the enzyme in the metabolic activation of aflatoxin B1
  Molecular Carcinogenesis, 1990
• Sodium fluoride is a less efficient human cell mutagen at low concentrations
  Environmental and Molecular Mutagenesis, 1990
• The induction of aneuploidy by nitrogen mustard in a human lymphoblastoid cell line
  Mutation Research Letters, 1987
• Mutagenicity of 1,2-dichloroethane and 1,2-dibromoethane in two human lymphoblastoid cell lines
  Mutation Research Letters, 1985
• Xenobiotic metabolism and mutation in a human lymphoblastoid cell line
  Chemico-Biological Interactions, 1985
• Assay for gene mutation in a human lymphoblast line, AHH-1, competent for xenobiotic metabolism
  Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 1984